Parts of the brain are connected to specific nerves that are connected to specific sex organs
The wiring connecting the correct part of the brain to the correct nerve to the correct part of the correct sex organ will not line up correctly
Actually you would not know how to signal any body part correctly because what you think signals one thing would signal another
This could result in death
This would be a problem with all brain transplants not just gender swap ones
@shortstories I know, its very difficult. A head transplant would be easier but still way more difficult. Each nerve would have to be individually connected to the correct corresponding nerve. Virtually impossible.